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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGK1
All Species:
50.3
Human Site:
Y274
Identified Species:
85.13
UniProt:
O00141
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00141
NP_001137148.1
431
48942
Y274
E
V
L
H
K
Q
P
Y
D
R
T
V
D
W
W
Chimpanzee
Pan troglodytes
XP_518751
605
68702
Y448
E
V
L
H
K
Q
P
Y
D
R
T
V
D
W
W
Rhesus Macaque
Macaca mulatta
XP_001102277
637
72261
Y480
E
V
L
H
K
Q
P
Y
D
R
T
V
D
W
W
Dog
Lupus familis
XP_849801
431
48950
Y274
E
V
L
H
K
Q
P
Y
D
R
T
V
D
W
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVC6
431
48910
Y274
E
V
L
H
K
Q
P
Y
D
R
T
V
D
W
W
Rat
Rattus norvegicus
Q06226
430
48909
Y274
E
V
L
H
K
Q
P
Y
D
R
T
V
D
W
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507569
431
48976
Y274
E
V
L
H
K
Q
P
Y
D
R
T
V
D
W
W
Chicken
Gallus gallus
Q6U1I9
432
48872
Y275
E
V
L
H
K
Q
P
Y
D
R
T
V
D
W
W
Frog
Xenopus laevis
Q6GLY8
434
49082
Y277
E
V
L
H
K
Q
P
Y
D
R
T
V
D
W
W
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
Y276
E
V
L
H
K
Q
P
Y
D
R
T
V
D
W
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INB9
611
68466
Y441
E
V
L
D
D
N
D
Y
G
Q
A
V
D
W
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q2PJ68
463
54273
L307
Y
L
A
P
E
I
I
L
K
K
P
Y
D
K
T
Sea Urchin
Strong. purpuratus
XP_001192139
440
49530
Y279
E
V
L
R
K
Q
E
Y
D
R
S
V
D
W
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P12688
680
76461
Y522
E
L
L
L
G
L
G
Y
T
K
A
V
D
W
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.7
66.2
97.6
N.A.
96.5
96.9
N.A.
95.3
95.1
88.9
86.6
N.A.
34.7
N.A.
47
62.7
Protein Similarity:
100
70.2
67.1
99
N.A.
98.6
98.6
N.A.
98.3
97.2
94.2
92.8
N.A.
47.9
N.A.
63.5
75
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
53.3
N.A.
6.6
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
60
N.A.
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
15
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
8
0
79
0
0
0
100
0
0
% D
% Glu:
93
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
72
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
79
0
0
0
8
15
0
0
0
8
0
% K
% Leu:
0
15
93
8
0
8
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
72
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
79
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
79
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
72
0
0
0
8
% T
% Val:
0
86
0
0
0
0
0
0
0
0
0
93
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
93
93
% W
% Tyr:
8
0
0
0
0
0
0
93
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _